AZITHROTECH CAPSULE 250mg (AZITHROMYCIN) PACK OF 6 CAPSULES

Azithrotech 250mg (Azithromycin) Comprehensive Guide

Composition:

Each capsule contains: Azithrotech Azithromycin (as dihydrate) U.S.P. 250mg (U.S.P. Specs.)

Presentation:

Each capsule contains: Azithromycin dihydrate U.S.P. equivalent to 250 mg of azithromycin

Properties:

Azithromycin belongs to the azalide group, a subset of the macrolide class of antibiotics. It exhibits a broad spectrum of activity against various bacteria, including Staphylococcus aureus, Streptococcus pneumoniae, Haemophilus influenzae, Escherichia coli, among others. Additionally, it displays effectiveness against certain sexually transmitted infections and other pathogens.

Pharmacokinetics:

After oral administration, Azithromycin is well-absorbed, showing an approximate bioavailability of 37%. It reaches peak plasma levels within approximately 2.3 hours, with a tissue depletion-related elimination half-life lasting 2 to 4 days. This antibiotic is highly tissue-bound, accumulating notably in target tissues such as the lungs, tonsils, and prostate.

Indications:

Azithromycin is indicated for treating various infections caused by susceptible organisms. These encompass lower respiratory tract infections, upper respiratory tract infections, skin and soft tissue infections, as well as mild to moderate typhoid fever. Additionally, it is effective against sexually transmitted infections caused by Chlamydia trachomatis.

Dosage and Administration:

The usual administration is a single dose, preferably on an empty stomach. The dosage varies based on the type of infection. Typically, healthcare providers administer a total dose of 1.5 g over 3 days for respiratory and skin infections. For sexually transmitted infections, they recommend a single 1 g dose.

Contraindications:

Patients with a known hypersensitivity to Azithromycin or any macrolide antibiotics should avoid using Azithromycin. It should also be avoided by patients with severe liver disease.

Precautions and Warnings:

Azithromycin use should be cautious in patients with renal or hepatic impairment. Its use during pregnancy should be considered only if no adequate alternatives exist. Limited data on its secretion in breast milk requires careful consideration during breastfeeding. Healthcare providers should be mindful of potential drug interactions.

Side Effects:

Generally well-tolerated, Azithromycin may cause mild to moderate side effects. Common ones include gastrointestinal symptoms like abdominal discomfort, vomiting, flatulence, diarrhea, and loose stools. Reports have also noted allergic reactions and reversible elevations in liver transaminases.

Overdosage:

Limited information exists on Azithromycin overdosage, but typical symptoms may include hearing loss, severe nausea, vomiting, and diarrhea. In cases of overdosage, gastric lavage and supportive measures are recommended.

Storage Conditions:

Store Azithromycin away from heat, light, and moisture, and keep it out of the reach of children.

Pack Size:

Capsules: 250 mg, 6 capsules in a blister pack.

This comprehensive guide provides information about Azithrotech 250mg (Azithromycin), including its composition, properties, indications, dosage, precautions, and more. Always consult with a healthcare professional for specific treatment recommendations.

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