PENCIRAL (Famciclovir): A Comprehensive Overview

Discover the intricacies of Penciral, a pharmaceutical formulation that leverages the efficacy of Famciclovir, an orally administered prodrug of the antiviral agent penciclovir Designed to combat various viral infections, Penciral stands as a promising solution in the field of antiviral medication Delve into the comprehensive description and valuable insights surrounding its pharmacological properties, uses, precautions, and more

Understanding the Composition and Description

Each filmcoated tablet of Penciral contains either 250mg or 500mg of Famciclovir USP Famciclovir, known as 2<2(2amino9Hpurin9yl)ethyl>1, propanediol diacetate, holds the molecular formula C14H19N504 and a molecular weight of 3213 This compound serves as a critical component in the fight against a range of viral infections, owing to its unique chemical properties

Exploring Pharmacological Properties and Mechanism of Action

Penciral's mechanism of action stems from the conversion of Famciclovir into penciclovir within the body This active compound demonstrates efficacy against various herpes simplex viruses, varicellazoster virus, Epstein
Barr virus, and cytomegalovirus Through competitive inhibition with deoxyguanosine triphosphate, penciclovir halts viral DNA chain elongation, effectively thwarting the replication of viral DNA

Insight into Pharmacokinetics and Absorption

Upon oral administration, Famciclovir is rapidly and extensively absorbed, subsequently converting to penciclovir The bioavailability of penciclovir post-administration was 77%, with peak plasma concentration occurring within a median time of 45 minutes post-dose Notably, the extent of systemic availability remains unaffected by food consumption

Applications and Indications

Penciral finds extensive use in treating various viral infections, including genital herpes, herpes labialis (cold sores), and herpes zoster (shingles) It is also employed for the treatment of recurrent episodes of orolabial or genital herpes in HIV-infected adults However, its efficacy for certain conditions may be subject to specific timeframes and recommended dosages, necessitating close monitoring under medical supervision

Navigating Precautions and Potential Interactions

While Penciral offers an effective solution, exercise caution, especially among pregnant and nursing individuals. Additionally, closely monitor patients with renal impairment or undergoing hemodialysis. Understanding potential drug interactions, particularly with probenecid and raloxifene, can help mitigate associated risks or adverse effects.

Contraindications and Necessary Warnings

Individuals with a known hypersensitivity to Famciclovir or any of the tablet's excipients should avoid using Penciral. Inappropriate dosing in patients with preexisting renal conditions has resulted in reported cases of acute renal failure, highlighting the necessity for tailored dosages. It's crucial to be aware of potential drug interactions and to carefully monitor patients to maximize the antiviral benefits of Penciral.

From its intricate composition to its nuanced pharmacological properties, Penciral stands as a promising pharmaceutical formulation in the realm of antiviral treatments With comprehensive knowledge and vigilant adherence to guidelines, Penciral presents a valuable resource in the fight against various viral infections

We strive to make your shopping experience seamless with fast and reliable delivery services! Here’s everything you need to know about our shipping and delivery policies:

Nationwide Shipping Offer

• Flat Rate Delivery: Enjoy nationwide delivery for just 299 PKR! (Limited time offer; subject to change without prior notice.)
• Free Shipping: Orders exceeding 5,000 PKR qualify for free delivery.

Order Processing

• Orders received during office hours are typically processed and dispatched on the same day.
• Orders placed after 5 PM will be shipped the following business day.

Delivery Timeline

• Punjab: Next business day delivery.
• Sindh & KPK: Typically delivered within 2 business days.
• Gilgit-Baltistan & Balochistan: Allow 3-4 business days for delivery.
  Delivery timelines are approximate and may vary depending on unforeseen circumstances.

Order Tracking

• Once your order is dispatched, you’ll receive a tracking number via email or WhatsApp.
• Track your shipment easily by visiting our website at www.dermatologists.pk/track or clicking the "Track Your Order" button on our homepage.

Important Information for Smooth Delivery

• Ensure your address is complete and accurate (include house number, landmarks, or references).
• Provide a primary phone number and an additional secondary contact number for the courier.
• In case of a failed delivery, you can request a reattempt by contacting us or coordinating directly with the courier service.

Reliable Courier Partners

We partner with TCS, M&P, and PostEx to ensure fast and dependable delivery to your location.

Thank you for choosing us! If you have any questions or need assistance, feel free to contact us anytime.