Renavel Tablets 800mg (10 Tablets) - Phosphate Binder for Dialysis Patients

Renavel Tablets 800mg contain sevelamer hydrochloride, a non-absorbable phosphate binder formulated to manage hyperphosphatemia in patients with chronic kidney disease (CKD) on dialysis. It effectively reduces phosphate absorption from food, preventing complications such as bone disorders and vascular calcification.

Mechanism of Action of Renavel Tablets 800mg

Sevelamer hydrochloride in Renavel Tablets 800mg works by binding to dietary phosphate in the gastrointestinal tract. This process prevents phosphate from being absorbed into the bloodstream, helping CKD patients maintain balanced phosphate levels. Unlike calcium-based phosphate binders, Renavel Tablets 800mg do not increase serum calcium levels, reducing the risk of hypercalcemia-related complications.

Indications and Uses

• Chronic Kidney Disease (CKD): Used in patients undergoing hemodialysis or peritoneal dialysis.
• Hyperphosphatemia Management: Helps control phosphate levels in CKD patients.
• Prevention of Bone and Cardiovascular Disorders: Reduces the risk of secondary hyperparathyroidism and vascular calcification.

Dosage and Administration

• The dosage of Renavel Tablets 800mg varies based on serum phosphate levels and should be determined by a healthcare professional.
• It is typically taken with meals to maximize phosphate binding.
• Tablets should be swallowed whole and not crushed, chewed, or split.

Precautions and Warnings

• Renavel Tablets 800mg should be used with caution in patients with gastrointestinal disorders such as dysphagia or bowel obstruction.
• Not recommended for patients with hypophosphatemia or known hypersensitivity to sevelamer hydrochloride.
• Regular monitoring of serum phosphate levels is essential during treatment.

Possible Side Effects

• Common side effects include nausea, vomiting, diarrhea, and constipation.
• Some patients may experience abdominal pain or flatulence.
• Rare but serious side effects include gastrointestinal obstruction or severe hypersensitivity reactions.

Drug Interactions

• Renavel Tablets 800mg may interact with other medications by altering their absorption.
• Should be taken separately from levothyroxine, ciprofloxacin, and anti-arrhythmic drugs to avoid reduced efficacy.

Storage and Handling

• Store at room temperature (15-30°C), away from moisture and direct sunlight.
• Keep out of reach of children.

Prescription Required

For more information, contact info@dermatologists.pk.

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