Dapsone Gel 5%: Effective Topical Treatment for Acne Vulgaris

Composition:

Each gram contains DAPSONE GEL 50 mg (as per innovator's specs)

Description:

• Dapsone: 4(4aminophenyl)sulfonyl aniline
• Molecular Formula: C12H12N2O2S
• Molecular Weight: 248.30

Indications:

Dapsone Gel 5% is indicated for the topical treatment of acne vulgaris

Dosage & Administration:

After the skin is gently washed and patted dry, apply approximately a pea sized amount of Gel 5% to the acne affected areas twice daily. Gently rub it in. If there is no improvement after 12 weeks, treatment with Gel 5% should be reassessed

Contraindications:

None

Adverse Effects:

Dapsone Gel 5% may cause serious side effects, including:

• Shortness of breath
• Tiredness or weakness
• Methemoglobinemia (contact a doctor immediately if lips, nail beds, or the inside of your mouth turn grey or blue)
• Dark brown urine
• Anemia (back pain, fever, yellow or pale skin)

Warning & Precautions:

• If there's no improvement after 12 weeks, treatment should be reassessed
• Common side effects include oiliness, peeling, dryness, and redness of the treated skin
• Methemoglobinemia risk, especially in patients with glucose6phosphate dehydrogenase deficiency
• Although peripheral neuropathy is a risk with oral Dapsone treatment, it is not a concern with topical Dapsone Gel 5%.
• Reports have emerged of skin reactions including toxic epidermal necrolysis, erythema multiforme, and others.

Drug Interactions:

• Potential interactions with certain medications like rifampin, anticonvulsants, St.
  John's Wort, and more
• Interaction with drugs that induce methemoglobinemia

Fertility, Pregnancy & Lactation:

• Pregnancy: Limited data available; consult a doctor
• Lactation: Minimal systemic absorption; effects on breastfed infants unknown
• Pediatric Use: Not recommended for children under 12
• Geriatric Use: Limited data for patients aged 65 and over

Overdosage:

If Dapsone Gel 5% comes in contact with the eyes, rinse immediately with cool water and contact a doctor if irritation persists

Presentation:

I hope this helps!

Instructions:

• Store at room temperature, protect from heat, light, and freezing temperatures
• Keep all medicines out of the reach of children

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