Terbiderm (Terbinafine Tablets USP) Oral Antifungal Agent

Composition:

• Terbiderm Forte Tablets
• Each tablet contains Terbinafine 250mg (as Terbinafine HCI
  BP)

Properties:

• Broadspectrum antifungal activity
• Fungicidal and fungistatic effects
• Targets dermatophytes, molds, and dimorphic fungi
• Interferes with fungal sterol biosynthesis
• Inhibits squalene epoxidase in fungal cell membrane
• Concentrates in skin, hair, and nails

Pharmacokinetics:

• Peak plasma
  concentrations achieved within 2 hours
• Moderately affected
  by food
• Strong binding to
  plasma proteins (99%)
• Rapid diffusion
  through the dermis and stratum corneum
• Secreted in sebum,
  achieving high concentrations in hair follicles
• Distributed into the
  nail plate in the first few weeks of therapy
• Eliminated through
  urine

Indications:

• Fungal infections of
  the skin, hair, and nails
• Dermatophytes
  (Trichophyton, Microsporum, Epidermophyton)
• Candida skin
  infections
• Onychomycosis (fungal
  nail infection)
• Not effective for
  pityriasis versicolor
• Dosage and Administration:
• Dosage varies by age
  group and indication
• Duration of treatment
  varies by the severity of the infection
• Best results when
  taken with meals
• Specific regimens for
  tinea corporis, cruris, pedis, cutaneous candidiasis, hair and scalp
  infections, and onychomycosis

Contraindications:

Hypersensitivity to
terbinafine

Precautions:

• Use with caution in
  patients with chronic liver dysfunction or impaired renal function
• Pregnancy: Use only
  if potential benefits outweigh risks
• Terbinafine is
  excreted in breast milk; avoid breastfeeding during oral treatment

Interactions:

• Negligible impact on
  drugs metabolized via the cytochrome P450 system
• Possible menstrual
  irregularities when used with oral contraceptives
• May be accelerated by
  drugs inducing metabolism or inhibited by drugs inhibiting cytochrome P450

Side Effects:

• Mild to moderate and
  transient
• Common side effects
  include gastrointestinal symptoms and nonserious skin reactions
• Rare cases of serious
  skin reactions, taste disturbances, and hepatobiliary dysfunction
• Isolated cases of
  hematological disorders (neutropenia, thrombocytopenia)

Overdosage:

• Rare, with reported
  cases of nausea, epigastric pain, and dizziness
• Treatment includes
  activated charcoal and symptomatic support

TERBIDERM FORTE TABLETS Facts:

• Terbinafine is a fastacting
  antifungal for skin and nail infections
• High cure rates (over
  90%) for dermatophyte infections
• Most effective in
  treating fungal nail infections within 3 to 6 months
• Regimen duration
  depends on the type and severity of infection
• Take terbinafine with
  meals for best results

• Follow your doctor's advice for a healthier, infectionfree
  life Terbiderm is your solution for fungal skin and nail infections

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Nationwide Shipping Offer

• Flat Rate Delivery: Enjoy nationwide delivery for just 299 PKR! (Limited time offer; subject to change without prior notice.)
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• Orders received during office hours are typically processed and dispatched on the same day.
• Orders placed after 5 PM will be shipped the following business day.

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• Sindh & KPK: Typically delivered within 2 business days.
• Gilgit-Baltistan & Balochistan: Allow 3-4 business days for delivery.
  Delivery timelines are approximate and may vary depending on unforeseen circumstances.

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